Yes, Kreg joinery can be used for make several joints, in a Hoosier Cabinetry (Hutch).
The pocket hole screws will make the construction easier.
There are definitely lots of places you can use Kreg Joints in a Hoosier cabinet: Joining the rails and stiles in the carcase frames, connecting the frames to the legs, attaching the bottom and intermediate panels, door frames, etc. If you're looking at a project that uses mortise and tenon or stub-mortise joints, you can almost always substitute in a Kreg Joint. Of course, you can use them in more places, but these are just a few.